Recent trend on fatty acid metabolism in the ischemic heart diseases.
نویسندگان
چکیده
منابع مشابه
"relationship between the disorders of glucose metabolism and ischemic heart diseases"
a study of the relationship between the disorder of glucose metabolism and ischemic heart disease was performed on 122 patients and 100 controls in loghman-dowleh adham’s medical center in tehran. the gtt abnormality was found in only 8% of the control group while for the patients with the heart ischemia the prevalence was 62.3%. prevalence of glucose metabolic disorder among men with acute myo...
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The effects of whole heart ischemia on fatty acid metabolism were studied in the isolated, perfused rat heart. A reduction in coronary flow and oxygen consumption resulted in lower rates of palmitate uptake and oxidation to CO2. This decrease in metabolic rate was associated with increased tissue levels of long chain acyl coenzyme A and long chain acylcarnitine. Cellular levels of acetyl-CoA, a...
متن کاملEffect of free fatty acids on myocardial function and metabolism in the ischemic dog heart.
Since elevation of plasma concentrations of free fatty acids (FFA) increases myocardial oxygen consumption without influencing mechanical performance in normal hearts, it was the purpose of this study to determine whether FFA would modify mechanical performance at limited oxygen supply. Left coronary blood flow was reduced by gradual clamping of a shunt from the left carotid artery until modera...
متن کاملFree fatty acid metabolism of the human heart at rest.
Myocardial substrate metabolism was studied in 13 subjects at the time of diagnostic cardiac catheterization by means of palmitic acid-(14)C infusion with arterial and coronary sinus sampling. Two subjects were considered free of cardiac pathology and all, with one exception, demonstrated lactate extraction across the portion of heart under study. Data for this single lactate-producing subject ...
متن کاملMetabolism of triglyceride fatty acid by the perfused rat heart.
1. Chyle lipids, labelled with (14)C, are taken up and oxidized by the isolated perfused rat heart. 2. In recirculatory perfusions, when chyle lipids are the sole exogenous energy source, about 24% of the total oxygen uptake is accounted for by their oxidation. This proportion is not changed by starvation of the rats for 48hr. and falls when an external work load is imposed on the left ventricl...
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ژورنال
عنوان ژورنال: Journal of Lipid Nutrition
سال: 1996
ISSN: 1883-2237,1343-4594
DOI: 10.4010/jln.5.23